15.8.14

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TYPE OF ARTICLE: REVIEW ARTICLE
TITLE: [Enter here the title of manuscript in sentence case.]

AUTHORS: [List here all author names; identify authors with author affiliations with superscript Arabic numerals]
[First Name Middle Name Family Name1, academic qualification]
[First Name Middle Name Family Name 1, academic qualification]
[First Name Middle Name Family Name 2, academic qualification]
[First Name Middle Name Family Name 2, academic qualification]
[First Name Middle Name Family Name 3, academic qualification]
[First Name Middle Name Family Name 3, academic qualification]

AFFILIATIONS: [List here all author affiliations including position in the department, department, institute, city, state, country, email; identify authors with author affiliations with superscript Arabic numerals]
1 [Author affiliations – position, department, institute, city, state, country, email ID]
2 [Author affiliations – position, department, institute, city, state, country, email ID]
3 Author affiliations – position, department, institute, city, state, country, email ID]

CORRESPONDING AUTHOR DETAILS
[Give here name, contact address, contact phone number, email and fax number of the corresponding author, Corresponding author must be one of the authors of the manuscript.]
[First Name   Middle Name   Family Name]
[Complete Mailing Address]
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OBJECTIVE: To assess factors influencing clinicians’ use of evidence based guidelines in relation to management of malaria in pregnancy.
METHODS: A descriptive cross-sectional survey was conducted to assess the factors affecting clinicians’ use of evidence based guidelines in management of malaria at Garissa Provincial Hospital, a level V referral facility in 2012. Purposive and convenient sampling were employed to incorporate the health workers interviewed in the study. Level of knowledge of the clinicians was scored against a standard guideline requirement tool. Both primary and secondary data were collected, recorded and analysed using SPSS version 17. 
RESULTS: Thirty six health care workers were interviewed; Eighty percent (80%) of them were aged 40 years and below and had more than 5 years of experience working at level V hospital. Eighty nine percent (89%) of clinicians had heard of the evidence based guidelines for treatment of malaria but only 17% were knowledgeable on the content of the guidelines. A small proportion, 25% of the clinicians accessed the guideline at point of use.  Of those who had heard of the guidelines, (80%) reported that CMEs were their main source of information. Fifty six percent (56.7%), 33.3% and 10% who were not knowledgeable on the guideline felt that lack of access clinical guidelines, lack of access to continuous medical education and lack of formal training in medical and nursing schools respectively as the major contributors to lack of knowledge and use of the guidelines. Level of professional qualification or duration of clinical experience did not significantly influence use of clinical guidelines (p= 0.596, p=0.641 respectively). Ninety four percent (94%), demonstrated willingness to effectively use the guidelines if properly guided. Data also showed, contrary to the guidelines, inappropriate use of antimalarial amongst cases with mild to moderate malaria with 88% of the cases having inadvertently received parenteral quinine instead of arthemether-lumafentrine (AL) or oral quinine.
CONCLUSION: There was a huge discrepancy between the acclaimed awareness vis a vis the use and practice of the malaria treatment guidelines. The main barriers to correct knowledge were lack of access to malaria guidelines at point of use, lack of access to CMEs and minimal formal training at medical schools. To improve on the management of malaria in pregnancy, provision of guidelines at point of care, programmes enhancing awareness through effective continuous medical education and proper pre-service training of health care workers are recommended.
References
1.      Cochrane AL. Effectiveness and Efficiency : Random Reflections on Health Services. London: Nuffield Provincial Hospitals Trust, 1972. Reprinted in 1989 in association with the BMJ. Reprinted in 1999 for Nuffield Trust by the Royal Society of Medicine Press, London, ISBN 1-85315-394-X.
2.      Schunemann HJ, Fretheim A, Oxman AD: Improving the use of research evidence in guideline development: 1. Guidelines for guidelines. Health Res Policy Syst 2006, 4:13
3.      Field MJ, Lohr KN. Clinical Practice Guidelines: Directions of a New Program. Washington, DC: National Academy Press,1990 .
4.      Steketee RW, Nahlen BL, Parise ME, Menendez C: The burden of malaria in pregnancy in malaria-endemic areas. Am J Trop Med Hyg 2001, 64:28-35.
5.      Brabin BJ. The risks and severity of malaria in pregnant women. In: Applied field in malaria reports, no. 1. Geneva, Switzerland: World Health Organization, 1991. 
6.      Kemri malaria fact sheet. http://www.kemri.org/index.php/help-desk/search/diseases-a-conditions/29-malaria/113-kenya-malaria-fact-sheet
7.      Ministry of Public health and Sanitation and Ministry of Medical services (2010): National Guidelines for the Diagnosis, treatment, and Prevention of Malaria in Kenya.
8.      Kenya Malaria indicator survey 2010. http://dhsprogram.com/pubs/pdf/MIS7/MIS7.pdf
9.      Davis DA, Taylor-Vaisey A: Translating guidelines into practice. A systematic review of theoretic concepts, practical experience and research evidence in the adoption of clinical practice guidelines.
10.   Ministry of Public health and Sanitation publication 2009. Towards malaria free Kenya. http://kenaam.org/wp-content/uploads/2013/04/KMPR_Final_report.pdf
11.   Tita A T, Selwyn B J, Waller D K, Kapadia A S, Dongmo S (2006): Factors associated with the awareness and practice of evidence-based obsteric care in an African setting. Fam Pract Manag; 11(2):51-58.
12.   Njama D, Dorsey G et’al (2003. Urban malaria: primary caregivers’ knowledge, attitudes, practices and predicators of malaria incidence in a cohort of Ugandan  children. In Trop Med and Int Health. Vol 8 No 8 pp: 685-692
13.   McKenna H, Ashton S, Keeney S: Barriers to evidence based practice in primary care: a review of the literature. Int J Nurs Stud 2004, 41(4):369-378.
14.   Adekunle A, Oyindamola B,  Falade O, Ikeoluwapo O,  Pagnoni F, 2011. Factors Associated with Use of Guideline in Home Management of Malaria among Children in Rural South West Nigeria. Malaria research and treatment, DOI: 10.4061/2011/701320
15.   Wasunna B, Zurovac D, Goodman C A, and Snow R W Why don't health workers prescribe ACTS? A qualitative study of factors affecting the prescription of artemether-lumefantrine, Malar J. 2008; 7: 29. 
16.   Al-Omari F.K, Al-Asmary S.M (2006): Attitude, awareness and practice of evidence based medicine among consultant’s physicians in Western region of Saudi Arabia; J Epidemiol community Health; 62:87
17.   National Health and Medical Research council. Clinical practice guidelines portal. http://www.clinicalguidelines.gov.au/
18.   Ukpe IS. Continuing medical education in unstable malaria areas. Bull World Health Organ 1999;77:948.
19.   Goulet F, Gagnon RJ, Desrosiers G, Jacques A, Sindon A. Participation in CME activities.  Can Fam Physician.1998;44:541-548.
20.   Grimshaw JM, Russell IT. Effect of clinical guidelines on medical practice: a systematic review of rigorous evaluations.  Lancet.1993;342:1317-1322.
21.   Davis DA, Taylor-Vaisey AL. Translating guidelines into practice: a systematic review of theoretic concepts, practical experience and research evidence in the adoption of clinical practice guidelines.  CMAJ.1997;157:408-416
22.   Clark NM, Gong M, Schork MA.  et al.  Impact of education for physicians on patient outcomes.  Pediatrics.1998;101:831-836.
23.   Curry L, Purkis IE. Validity of self-reports of behavior changes by participants after a CME course.  J Med Educ.1986;61:579-584.
24.   Parboosingh J, Gondocz ST. The Maintenance of Competence Program (MOCOMP): motivating specialists to appraise the quality of their continuing medical education activities.  Can J Surg.1993;36:29-32.
25.   Scott IA, Denaro CP, Bennett CJ, Mudge AM: Towards more effective use of decision support in clinical practice: what the guidelines for guidelines don't tell you. Intern Med J 2004, 34(8):492-500.
26.   Randell R, Mitchell N, Thompson C, McCaughan D, Dowding D: Supporting nurse decision making in primary care: exploring use of and attitude to decision tools. Health Informatics J 2009, 15(1):5-16.


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TYPE OF ARTICLE: REVIEW ARTICLE
TITLE: [Enter here the title of manuscript in sentence case.]

AUTHORS: [List here all author names; identify authors with author affiliations with superscript Arabic numerals]
[First Name Middle Name Family Name1, academic qualification]
[First Name Middle Name Family Name 1, academic qualification]
[First Name Middle Name Family Name 2, academic qualification]
[First Name Middle Name Family Name 2, academic qualification]
[First Name Middle Name Family Name 3, academic qualification]
[First Name Middle Name Family Name 3, academic qualification]

AFFILIATIONS: [List here all author affiliations including position in the department, department, institute, city, state, country, email; identify authors with author affiliations with superscript Arabic numerals]
1 [Author affiliations – position, department, institute, city, state, country, email ID]
2 [Author affiliations – position, department, institute, city, state, country, email ID]
3 Author affiliations – position, department, institute, city, state, country, email ID]

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